The full-fledged US-China trade war that began in 2018 has led to several pieces of evidence that suggest the bilateral relationship that, up until now, was based on both competition and cooperation, has now entered a phase where strategic competition is its defining characteristic. The recent US-China relationship is complicated because it involves a global hegemony competition that has followed China’s rise. The relationship is one that involves the structure of international politics and time will be required to resolve the issues that the relationship faces. There is an imperative to analyze the current situation through a perspective of confrontation that is centered on the core interests of both sides. Cross-strait relations issue are very important hotspots that may be the site of real clashes between the Chinese and the Americans. The basic issues and contradictions inherent to the current Sino-American relationship include the following: 1) from a political and diplomatic perspective, the issues of travel to Taiwan, National Defense Authorization Act and Taiwan Assurance Act issue; 2) from a military perspective, the blockading of China by the US through its Indo-Pacific strategy and freedom of navigation strategy in the South China Sea; and, 3) from an economic perspective, the “Belt and Road” policy and the trade war between China and the US to dominate advanced fields of technology. Of course, while the two countries are clashing due to the contradictions that have emerged from these basic issues, China and the US are still coexisting under the framework of competition and cooperation, in contrast to the confrontational relationship that existed between the US and the Soviet Union during the Cold War. This means that the US-China relationship is not a zero-sum game and that there is space for the two countries to cooperate across many different spheres. From China’s perspective, the aim is to complete unification of the country. Chinese leaders believe that the goal is peaceful unification and desire avoiding unification by force, yet focus on the “feelings of the people” and believe that the barrier to unification is the US. The Taiwan issue is a very big card that the US can play to put China in line. The issue involves both country’s interests and neither can abandon it. Taiwan is like an “unsinkable aircraft carrier” to the US, and, to China, “territory that must be reunified with the mainland.” Both the US and China cannot back down on the issue. In short, there are four phenomena that will not change in regards to US and Chinese involvement in Taiwan. As a result, as long as the US and Taiwan maintain their current policies, China will be forced to maintain a hardline response toward them.